GRM2 antibody (AA 915-924)

Catalog No. ABIN1496054

Product Details anti-GRM2 Antibody

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Binding Specificity: AA 915-924

Reactivity: Human, Rat, Mouse, Dog, Cow, Rabbit, Hamster, Monkey, Bat, Horse

Host: Goat

Clonality: Polyclonal

Conjugate: This GRM2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human GRM2 / MGLUR2. This antibody is expected to recognize both isoforms (NP_000830.2, NP_001123535.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit (100%) Platypus (90%) Mosquito, Sea anemone (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KETAPERREV from an internal region of human GRM2 / MGLUR2 (NP_000830.2, NP_001123535.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit (100%), Platypus (90%), Mosquito, Sea anemone (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:16000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 30kD band observed in Human Brain (Hippocampus) lysates (calculated MW of 27.5kD according to NP_001123535.1). Recommended concentration: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GRM2

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Alternative Name: GRM2 / MGLUR2 (GRM2 Products)

Synonyms: GLUR2 antibody, GPRC1B antibody, MGLUR2 antibody, mGlu2 antibody, 4930441L02Rik antibody, Gprc1b antibody, mGluR2 antibody, mGluR7 antibody, glutamate metabotropic receptor 2 antibody, glutamate receptor, metabotropic 2 antibody, GRM2 antibody, Grm2 antibody

Background: Name/Gene ID: GRM2
Subfamily: Metabotropic glutamate
Family: GPCR

Synonyms: GRM2, Glutamate receptor homolog, GPRC1B, MGlu2, Metabotropic, GLUR2, MGLUR2

Gene ID: 2912

NCBI Accession: NP_000830, NP_001123535

UniProt: Q14416

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport