RPS6KA3 antibody (pThr359)

Catalog No. ABIN1531362

Product Details anti-RPS6KA3 Antibody

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Binding Specificity: AA 331-380, pThr359

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity:

p90 RSK (Phospho-Thr359+Ser363) Antibody detects endogenous levels of p90 RSK only when phosphorylated at Thr359 and Ser363.

PhosphorylationH:T359/S363 M:S352/T348 R:S363/T359

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human p90 RSK around the phosphorylation site of Thr359 and Ser363.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.149957 (NCBI Gene Symbol: RPS6KA1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for RPS6KA3

Target: RPS6KA3 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 3 (RPS6KA3))

Alternative Name: p90 RSK (RPS6KA3 Products)

Synonyms: HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, CLS antibody, HU-3 antibody, ISPK-1 antibody, MAPKAPK1B antibody, MRX19 antibody, RSK2 antibody, S6K-alpha3 antibody, p90-RSK2 antibody, pp90RSK2 antibody, MPK-9 antibody, Rsk2 antibody, RGD1563860 antibody, id:ibd1103 antibody, rps6ka3 antibody, si:ch211-114c12.12 antibody, wu:fk86e02 antibody, zgc:56006 antibody, zgc:158386 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase A3 antibody, ribosomal protein S6 kinase polypeptide 3 antibody, ribosomal protein S6 kinase a, polypeptide 3a antibody, ribosomal protein S6 kinase, polypeptide 3b antibody, RPS6KA1 antibody, RPS6KA3 antibody, Rps6ka3 antibody, rps6ka3a antibody, rps6ka3b antibody

Background:

Synonyms: 90 kDa ribosomal protein S6 kinase 1, kinase p90RSK1, KS6A1, KS6AA, MAPKAP-K1a, p90-RSK 1, pp90RSK1, Ribosomal protein S6 kinase alpha 1, Ribosomal S6 kinase 1, RPS6KA1, RSK-1, RSK1, S6K-alpha 1

NCBI Gene Symbol: RPS6KA1

Molecular Weight: 82 kDa

Gene ID: 6195

OMIM: 601684

UniProt: Q15418

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades