MEK1/2 antibody (pSer222)
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- Target See all MEK1/2 (MAP2K1/2) products
- MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))
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Binding Specificity
- AA 193-242, pSer222
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MEK1/2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
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MEK1/2 (Phospho-Ser221) Antibody detects endogenous levels of MEK1/2 only when phosphorylated at Ser221.
PhosphorylationH:S222/226 M:S222/226 R:S222/226
- Purification
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
- Purity
- > 95 %
- Immunogen
- The antiserum was produced against synthesized peptide derived from human MEK1/2 around the phosphorylation site of Ser221.
- Isotype
- IgG
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- Application Notes
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
- Comment
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Unigene-Number: Hs.145442, Hs.465627 (NCBI Gene Symbol: MAP2K2)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Stable at -20°C for at least 1 year.
- Expiry Date
- 12 months
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- Target
- MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))
- Alternative Name
- MEK1/2 (MAP2K1/2 Products)
- Background
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Synonyms: Dual specificity mitogen-activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1, MAP2K1, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK1, MP2K1, PRKMK1, kinase MEK1
NCBI Gene Symbol: MAP2K2
- Molecular Weight
- 43 kDa
- Gene ID
- 5604, 5605
- OMIM
- 115150
- UniProt
- Q02750, P36507
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