BAD antibody (Cleaved-Asp71)

Catalog No. ABIN1536078

This Rabbit Polyclonal antibody specifically detects BAD in WB, ELISA and IHC. It exhibits reactivity toward Mouse and Rat.

Quick Overview for BAD antibody (Cleaved-Asp71) (ABIN1536078)

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-BAD Antibody

Binding Specificity: AA 21-70, Cleaved-Asp71

Specificity:

BAD (Cleaved-Asp71) Antibody detects endogenous levels of fragment of activated BAD resulting from cleavage adjacent to Asp71.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from mouse BAD.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Mm.4387 (NCBI Gene Symbol: Bad)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for BAD

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Alternative Name: BAD

Background:

Synonyms: BBC2, BCL2L8, BCL-X/BCL-2 binding protein, BCL2 ANTAGONIST OF CELL DEATH, BCL2-antagonist of cell death protein, BCL2-binding component 6, BCL2-binding protein

NCBI Gene Symbol: Bad

Molecular Weight: 20 kDa

Gene ID: 12015

UniProt: Q61337

Pathways: MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events