GFR antibody (C-Term)

Catalog No. ABIN1537440

Product Details anti-GFR Antibody

Target: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Binding Specificity: AA 529-555, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFR antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAPGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-555 amino acids from the C-terminal region of human RAPGEF5.

Clone: RB36938

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RAPGEF5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for GFR

Target: GFR (RAPGEF5) (Rap Guanine Nucleotide Exchange Factor (GEF) 5 (RAPGEF5))

Alternative Name: RAPGEF5 (RAPGEF5 Products)

Synonyms: GFR antibody, MR-GEF antibody, REPAC antibody, 4932413M22 antibody, C86120 antibody, D030051B22Rik antibody, Mrgef antibody, mKIAA0277 antibody, mmr-gef antibody, RGD1562891 antibody, rMR-GEF antibody, MGC154311 antibody, Rap guanine nucleotide exchange factor 5 antibody, Rap guanine nucleotide exchange factor (GEF) 5 antibody, Rap guanine nucleotide exchange factor 5 S homeolog antibody, RAPGEF5 antibody, Rapgef5 antibody, rapgef5.S antibody

Background: Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).

Molecular Weight: 67733

Gene ID: 9771

NCBI Accession: NP_036426

UniProt: Q92565

Pathways: RTK Signaling, Neurotrophin Signaling Pathway, Hepatitis C