This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ABCC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-669 amino acids from the Central region of human ABCC9.
SUR2B antibody, DDBDRAFT_0215814 antibody, DDBDRAFT_0216237 antibody, DDB_0215814 antibody, DDB_0216237 antibody, si:dkey-183c2.3 antibody, sur2 antibody, ABC37 antibody, ATFB12 antibody, CANTU antibody, CMD1O antibody, SUR2 antibody, SUR2A antibody, AI414027 antibody, AI449286 antibody, Sur2 antibody, ABCC9 antibody, ATP binding cassette subfamily C member 9 antibody, ATP-binding cassette sub-family C member 8 antibody, ABC transporter C family protein antibody, ATP-binding cassette sub-family C member 9 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 9 antibody, ABCC9 antibody, LOC581821 antibody, abcC9 antibody, LOC100470981 antibody, abcc9 antibody, Abcc9 antibody
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.