SMPD3 antibody (N-Term)

Catalog No. ABIN1539047

Product Details anti-SMPD3 Antibody

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Binding Specificity: AA 137-165, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMPD3 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SMPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the N-terminal region of human SMPD3.

Clone: RB39878

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SMPD3 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for SMPD3

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Alternative Name: SMPD3 (SMPD3 Products)

Synonyms: 4631433G07Rik antibody, AI427456 antibody, AW537966 antibody, fro antibody, nSMase2 antibody, cca1 antibody, NSMASE2 antibody, sphingomyelin phosphodiesterase 3 antibody, sphingomyelin phosphodiesterase 3, neutral antibody, SMPD3 antibody, Smpd3 antibody

Background: SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Molecular Weight: 71081

Gene ID: 55512

NCBI Accession: NP_061137

UniProt: Q9NY59

Pathways: Hormone Transport