PDK4 antibody

Catalog No. ABIN1539836

The Mouse Monoclonal anti-PDK4 antibody is suitable to detect PDK4 in samples from Human and Mouse. It has been validated for WB.

Quick Overview for PDK4 antibody (ABIN1539836)

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDK4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 345CT19-6-2

Product Details anti-PDK4 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged PDK4 protein(Fragment) was used to produced this monoclonal antibody.

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000. WB: 1:500-1:1000. WB: 1:250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PDK4 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for PDK4

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Alternative Name: PDK4

Background: This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

Molecular Weight: 46469

Gene ID: 5166

NCBI Accession: NP_002603

UniProt: Q16654

Pathways: PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect