PDK4 antibody (AA 1-411)

Catalog No. ABIN518762

There are 2+ publications for this product available. The Mouse Monoclonal anti-PDK4 antibody is suitable to detect PDK4 in samples from Human. It has been validated for ELISA.

Quick Overview for PDK4 antibody (AA 1-411) (ABIN518762)

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDK4 antibody is un-conjugated

Application: ELISA

Clone: 1A10

Product Details anti-PDK4 Antibody

Binding Specificity: AA 1-411

Purpose: Mouse monoclonal antibody raised against a full length recombinant PDK4.

Sequence: MKAARFVLRS AGSLNGAGLV PREVEHFSRY SPSPLSMKQL LDFGSENACE RTSFAFLRQE LPVRLANILK EIDILPTQLV NTSSVQLVKS WYIQSLMDLV EFHEKSPDDQ KALSDFVDTL IKVRNRHHNV VPTMAQGIIE YKDACTVDPV TNQNLQYFLD RFYMNRISTR MLMNQHILIF SDSQTGNPSH IGSIDPNCDV VAVVQDAFEC SRMLCDQYYL SSPELKLTQV NGKFPDQPIH IVYVPSHLHH MLFELFKNAM RATVEHQENQ PSLTPIEVIV VLGKEDLTIK ISDRGGGVPL RIIDRLFSYT YSTAPTPVMD NSRNAPLAGF GYGLPISRLY AKYFQGDLNL YSLSGYGTDA IIYLKALSSE SIEKLPVFNK SAFKHYQMSS EADDWCIPSR EPKNLAKEVA M

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PDK4 (AAH40239.1, 1 a.a. ~ 411 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PDK4 antibody (ABIN518762)

Harada, Kakuda, Sato, Ikeda, Shimoda, Yamamoto, Inoue, Ohta, Kasashima, Kawashima, Nakanuma: "Alteration of energy metabolism in the pathogenesis of bile duct lesions in primary biliary cirrhosis." in: Journal of clinical pathology, Vol. 67, Issue 5, pp. 396-402, (2014) (PubMed).

Puthanveetil, Wang, Wang, Kim, Abrahani, Rodrigues: "The increase in cardiac pyruvate dehydrogenase kinase-4 after short-term dexamethasone is controlled by an Akt-p38-forkhead box other factor-1 signaling axis." in: Endocrinology, Vol. 151, Issue 5, pp. 2306-18, (2010) (PubMed).

Target Details for PDK4

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Alternative Name: PDK4

Background: Full Gene Name: pyruvate dehydrogenase kinase, isozyme 4
Synonyms: FLJ40832

Gene ID: 5166

Pathways: PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect