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PDK4 antibody (AA 382-410)

PDK4 Reactivity: Human, Mouse WB, ELISA, IHC, IF, mIHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3028963
  • Target See all PDK4 Antibodies
    PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
    Binding Specificity
    • 15
    • 14
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 382-410
    Reactivity
    • 72
    • 46
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 71
    • 13
    Rabbit
    Clonality
    • 75
    • 11
    Polyclonal
    Conjugate
    • 44
    • 9
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDK4 antibody is un-conjugated
    Application
    • 76
    • 49
    • 27
    • 13
    • 13
    • 10
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Multiplex Immunohistochemistry (mIHC)
    Purification
    Purified
    Immunogen
    A portion of amino acids 382-410 from the human protein was used as the immunogen for this PDK4 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PDK4 Primary Antibody
  • Application Notes
    Titration of the PDK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:100,Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the PDK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Sirait-Fischer, Olesch, Fink, Berkefeld, Huard, Schmid, Takeda, Brüne, Weigert: "Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model." in: Frontiers in oncology, Vol. 10, pp. 1771, (2020) (PubMed).

  • Target
    PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
    Alternative Name
    PDK4 (PDK4 Products)
    Synonyms
    AV005916 antibody, pyruvate dehydrogenase kinase 4 antibody, pyruvate dehydrogenase kinase, isoenzyme 4 antibody, pdk4 antibody, PDK4 antibody, Pdk4 antibody
    Background
    PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
    UniProt
    Q16654
    Pathways
    PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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