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ATP6V1E1 antibody (AA 77-226)
ATP6V1E1
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ATP6V1E1 Antibody
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Target
See all ATP6V1E1 Antibodies
ATP6V1E1
(ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))
Binding Specificity
All epitopes for ATP6V1E1 antibodies
AA 77-226
Reactivity
All reactivities for ATP6V1E1 antibodies
Human
Host
All hosts for ATP6V1E1 antibodies
Rabbit
Clonality
All clonalities for ATP6V1E1 antibodies
Polyclonal
Conjugate
All conjugates for ATP6V1E1 antibodies
This ATP6V1E1 antibody is un-conjugated
Application
All applications for ATP6V1E1 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Sequence
NQARLKVLRA RDDLITDLLN EAKQRLSKVV KDTTRYQVLL DGLVLQGLYQ LLEPRMIVRC RKQDFPLVKA AVQKAIPMYK IATKNDVDVQ IDQESYLPED IAGGVEIYNG DRKIKVSNTL ESRLDLIAQQ MMPEVRGALF GANANRKFLD
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 77-226 of human ATP6V1E1 (NP_001687.1).
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for ATP6V1E1
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Target
ATP6V1E1
(ATPase, H+ Transporting, Lysosomal 31kDa, V1 Subunit E1 (ATP6V1E1))
Alternative Name
ATP6V1E1 (ATP6V1E1 Products )
Synonyms
ATP6E antibody, ATP6E2 antibody, ATP6V1E antibody, P31 antibody, Vma4 antibody, 2410029D23Rik antibody, Atp6e antibody, Atp6e2 antibody, Atp6v1e antibody, D6Ertd385e antibody, E2 antibody, T22B4.130 antibody, T22B4_130 antibody, TUFF antibody, V-ATPase subunit E1 antibody, VACUOLAR H+-ATPASE SUBUNIT E ISOFORM 1 antibody, VHA-E1 antibody, emb2448 antibody, embryo defective 2448 antibody, vacuolar ATP synthase subunit E1 antibody, atp6e antibody, atp6v1e1 antibody, chunp6932 antibody, fj35f08 antibody, wu:fj35f08 antibody, ATPase H+ transporting V1 subunit E1 antibody, ATPase, H+ transporting, lysosomal V1 subunit E1 antibody, vacuolar ATP synthase subunit E1 antibody, ATPase, H+ transporting, lysosomal, V1 subunit E1b antibody, ATP6V1E1 antibody, Atp6v1e1 antibody, atp6v1e1 antibody, TUF antibody, atp6v1e1b antibody
Background
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome.,ATP6V1E1,ATP6E,ATP6E2,ATP6V1E,P31,Vma4,ARCL2C,Cancer,Signal Transduction,Endocrine & Metabolism,ATP6V1E1
Molecular Weight
22 kDa/23 kDa/26 kDa
Gene ID
529
UniProt
P36543
Pathways
Transition Metal Ion Homeostasis , Proton Transport
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