DYNLT1 antibody (AA 1-113)

Catalog No. ABIN1679625

Product Details anti-DYNLT1 Antibody

Target: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Binding Specificity: AA 1-113

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNLT1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MEDYQAAEET AFVVDEVSNI VKEAIESAIG GNAYQHSKVN QWTTNVVEQT LSQLTKLGKP FKYIVTCVIM QKNGAGLHTA SSCFWDSSTD GSCTVRWENK TMYCIVSAFG LSI

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human DYNLT1 (NP_006510.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DYNLT1

Target: DYNLT1 (Dynein, Light Chain, Tctex-Type 1 (DYNLT1))

Alternative Name: DYNLT1 (DYNLT1 Products)

Synonyms: cw-1 antibody, tctel1 antibody, dynlt1a antibody, tctex-1 antibody, MGC85297 antibody, tctex1 antibody, Ci-LC3 antibody, CW-1 antibody, TCTEL1 antibody, AGS2 antibody, Tctex1 antibody, dynein light chain Tctex-type 1 L homeolog antibody, dynein light chain Tctex-type 1 antibody, dynein, light chain, Tctex-type 1 antibody, dynlt1.L antibody, DYNLT1 antibody, dynlt1 antibody, Dynlt1 antibody

Background: This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms.,DYNLT1,CW-1,TCTEL1,tctex-1,DYNLT1

Molecular Weight: 12 kDa

Gene ID: 6993

UniProt: P63172

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling