E2F2 antibody
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- Target See all E2F2 Antibodies
- E2F2 (E2F Transcription Factor 2 (E2F2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This E2F2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthesized peptide derived from human E2F2
- Isotype
- IgG
- Top Product
- Discover our top product E2F2 Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- E2F2 (E2F Transcription Factor 2 (E2F2))
- Alternative Name
- E2F2 (E2F2 Products)
- Synonyms
- E2F-2 antibody, CG1071 antibody, Dmel\\CG1071 antibody, E2F antibody, E2F2 antibody, dE2F-2 antibody, dE2F2 antibody, dE2f2 antibody, de2f2 antibody, e2f2 antibody, 9230110J10 antibody, E130207A07 antibody, fb40b03 antibody, wu:fb40b03 antibody, E2F transcription factor 2 antibody, si:ch211-160f23.5 antibody, E2F2 antibody, E2f2 antibody, si:ch211-160f23.5 antibody
- Background
- The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46 % amino acid identity to E2F1. [provided by RefSeq, Jul 2008],E2F-2,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,Signal Transduction,Transcription Factors,E2F2
- Molecular Weight
- 47 kDa
- Gene ID
- 1870
- UniProt
- Q14209
- Pathways
- Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication
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