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NAE1 antibody (AA 1-220)
NAE1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-NAE1 Antibody
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Target
See all NAE1 Antibodies
NAE1
(NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
Binding Specificity
All epitopes for NAE1 antibodies
AA 1-220
Reactivity
All reactivities for NAE1 antibodies
Human
Host
All hosts for NAE1 antibodies
Rabbit
Clonality
All clonalities for NAE1 antibodies
Polyclonal
Conjugate
All conjugates for NAE1 antibodies
This NAE1 antibody is un-conjugated
Application
All applications for NAE1 antibodies
Western Blotting (WB)
Sequence
MAQLGKLLKE QKYDRQLRLW GDHGQEALES AHVCLINATA TGTEILKNLV LPGIGSFTII DGNQVSGEDA GNNFFLQRSS IGKNRAEAAM EFLQELNSDV SGSFVEESPE NLLDNDPSFF CRFTVVVATQ LPESTSLRLA DVLWNSQIPL LICRTYGLVG YMRIIIKEHP VIESHPDNAL EDLRLDKPFP ELREHFQSYD LDHMEKKDHS HTPWIVIIAK
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NAE1 (NP_003896.1).
Isotype
IgG
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Discover our top product NAE1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:1000 - 1:4000
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for NAE1
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Target
NAE1
(NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
Alternative Name
NAE1 (NAE1 Products )
Synonyms
APPBP1 antibody, CG7828 antibody, Dmel\\CG7828 antibody, anon-WO0140519.225 antibody, dAPP-BP1 antibody, dAPPBP1 antibody, A-116A10.1 antibody, ula-1 antibody, Appbp1 antibody, 59kDa antibody, appbp1 antibody, zgc:66148 antibody, beta-Amyloid precursor protein binding protein 1 antibody, NEDD8 activating enzyme E1 subunit 1 antibody, NEDD8 activating enzyme E1 subunit 1 S homeolog antibody, nedd8 activating enzyme E1 subunit 1 antibody, NEDD8-activating enzyme E1 regulatory subunit antibody, APP-BP1 antibody, NAE1 antibody, Nae1 antibody, nae1.S antibody, nae1 antibody, ula-1 antibody
Background
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.,NAE1,A-116A10.1,APPBP1,HPP1,ula-1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Neuroscience,Neurodegenerative Diseases,NAE1
Molecular Weight
50 kDa/59 kDa/60 kDa
Gene ID
8883
UniProt
Q13564
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