Angiotensin II Type 2 Receptor antibody

Catalog No. ABIN7101542

Product Details anti-Angiotensin II Type 2 Receptor Antibody

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Angiotensin II Type 2 Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human AGTR2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Angiotensin II Type 2 Receptor

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Alternative Name: AGTR2 (AGTR2 Products)

Synonyms: AT2 antibody, ATGR2 antibody, MRX88 antibody, AI316812 antibody, AW107640 antibody, AT2-R antibody, AT2R antibody, AT₂R antibody, at2 antibody, zgc:113016 antibody, AGTR2 antibody, angiotensin II receptor type 2 antibody, angiotensin II receptor, type 2 antibody, AGTR2 antibody, Agtr2 antibody, agtr2 antibody

Background: The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation. [provided by RefSeq, Jan 2010],AT2, ATGR2, MRX88,Apoptosis,Blood,Blood_Blood Pressure regulation,Cardiovascular,Cell Biology & Developmental Biology,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Signal Transduction,AGTR2

Molecular Weight: 41 kDa

Gene ID: 186

UniProt: P50052

Pathways: ACE Inhibitor Pathway, Hormone Transport, Regulation of Systemic Arterial Blood Pressure by Hormones