TIE1 antibody (AA 350-600)

Catalog No. ABIN1683033

Product Details anti-TIE1 Antibody

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Binding Specificity: AA 350-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIE1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IPQILNMASE LEFNLETMPR INCAAAGNPF PVRGSIELRK PDGTVLLSTK AIVEPEKTTA EFEVPRLVLA DSGFWECRVS TSGGQDSRRF KVNVKVPPVP LAAPRLLTKQ SRQLVVSPLV SFSGDGPIST VRLHYRPQDS TMDWSTIVVD PSENVTLMNL RPKTGYSVRV QLSRPGEGGE GAWGPPTLMT TDCPEPLLQP WLEGWHVEGT DRLRVSWSLP LVPGPLVGDG FLLRLWDGTR GQERRENVSS P

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human TIE1 (NP_005415.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TIE1

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Alternative Name: TIE1 (TIE1 Products)

Synonyms: JTK14 antibody, TIE antibody, D430008P04Rik antibody, tie-1 antibody, tyrosine kinase with immunoglobulin like and EGF like domains 1 antibody, tyrosine kinase with immunoglobulin-like and EGF-like domains 1 antibody, tyrosine-protein kinase receptor Tie-1 antibody, endothelium-specific receptor tyrosine kinase 1 antibody, TIE1 antibody, Tie1 antibody, CpipJ_CPIJ018933 antibody, tie1 antibody

Background: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,TIE1,JTK14,TIE,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Stem Cells,Endothelial Progenitors,Cardiovascular,TIE1

Molecular Weight: 34 kDa/40 kDa/125 kDa

Gene ID: 7075

UniProt: P35590

Pathways: RTK Signaling