PUM2 antibody (AA 901-1066) (Alexa Fluor 350)
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- Target See all PUM2 Antibodies
- PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))
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Binding Specificity
- AA 901-1066
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PUM2 antibody is conjugated to Alexa Fluor 350
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Pumilio 2
- Isotype
- IgG
- Top Product
- Discover our top product PUM2 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PUM2 (Pumilio Homolog 2 (Drosophila) (PUM2))
- Alternative Name
- Pumilio 2 (PUM2 Products)
- Synonyms
- pum-2 antibody, 5730503J23Rik antibody, Pumm2 antibody, mKIAA0235 antibody, PUMH2 antibody, PUML2 antibody, pumilio RNA binding family member 2 antibody, pumilio RNA-binding family member 2 antibody, pum2 antibody, Pum2 antibody, PUM2 antibody
- Background
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Synonyms: FLJ36528, KIAA0235, MGC138251, MGC138253, PUM 2, Pum2, PUM2, PUMH2, Pumilio Drosphila homolog 2, Pumilio homolog 2 Drosophila, Pumilio homolog 2, Pumilio2, PUM2_HUMAN.
Background: Pumilio 2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding mRNA targets. It supports proliferation and self-renewal of stem cells by regulating the translation of key transcripts. The Pumilio gene encodes proteins that are required for development of germ stem cells in one or both sexes. The Pumilio protein interacts with the human Nanos1 protein and this interaction may play a conserved role in germ cell development. Pumilio 2 is highly expressed in testis and ovary and at lower levels in brain, heart, kidney, liver, muscle, placenta, intestine and stomach. It is also expressed in stem cells, germ cells and in most fetal tissues.
- Gene ID
- 23369
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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