FZD3 antibody (AA 121-220) (Cy7)
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- Target See all FZD3 Antibodies
- FZD3 (Frizzled Family Receptor 3 (FZD3))
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Binding Specificity
- AA 121-220
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Reactivity
- Human, Mouse, Rat, Xenopus laevis
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FZD3 antibody is conjugated to Cy7
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FZD3/Frizzled 3
- Isotype
- IgG
- Top Product
- Discover our top product FZD3 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FZD3 (Frizzled Family Receptor 3 (FZD3))
- Alternative Name
- FZD3/Frizzled 3 (FZD3 Products)
- Synonyms
- Fz-3 antibody, FZ-3 antibody, fz3 antibody, Xfz3 antibody, frz3 antibody, hfz3 antibody, frz-3 antibody, frizzled3 antibody, frizzled-3 antibody, FZD3 antibody, AU020229 antibody, D930050A07Rik antibody, Fz3 antibody, fz9 antibody, fzd3 antibody, zg09 antibody, fzd3l antibody, frizzled class receptor 3 antibody, frizzled class receptor 3 L homeolog antibody, frizzled class receptor 3a antibody, frizzled class receptor 3b antibody, FZD3 antibody, fzd3 antibody, fzd3.L antibody, Fzd3 antibody, fzd3a antibody, fzd3b antibody
- Background
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Synonyms: Fz-3, Frizzled-3, hFz3, FZD3
Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
- Gene ID
- 7976
- UniProt
- Q9NPG1
- Pathways
- WNT Signaling, Tube Formation
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