alpha Adducin antibody (pThr445)
-
- Target See all alpha Adducin (ADD1) Antibodies
- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
-
Binding Specificity
- pThr445
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This alpha Adducin antibody is un-conjugated
-
Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Thr445
- Isotype
- IgG
- Top Product
- Discover our top product ADD1 Primary Antibody
-
-
- Application Notes
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
- Alternative Name
- alpha Adducin (ADD1 Products)
- Synonyms
- ADDA antibody, AI256389 antibody, alpha-adducin antibody, bZ1H20.1 antibody, cb787 antibody, zgc:158352 antibody, add2 antibody, adda antibody, add1-a antibody, ADD1 antibody, adducin 1 antibody, adducin 1 (alpha) antibody, adducin 1 S homeolog antibody, ADD1 antibody, Add1 antibody, add1 antibody, add1.S antibody
- Background
-
Synonyms: Adducin phospho T445, p-Adducin phospho T445, ADD1, ADDA, Adducin 1 alpha, Adducin 1, Alpha adducin, ADDA_HUMAN.
Background: Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.
- Gene ID
- 118
- UniProt
- P35611
- Pathways
- Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
-