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CLP1 antibody (AA 1-100)

CLP1 Reactivity: Human WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1714385
  • Target See all CLP1 Antibodies
    CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
    Binding Specificity
    • 14
    • 8
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 49
    • 12
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 45
    • 4
    Rabbit
    Clonality
    • 47
    • 2
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLP1 antibody is un-conjugated
    Application
    • 42
    • 18
    • 12
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HEAB
    Isotype
    IgG
    Top Product
    Discover our top product CLP1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
    Alternative Name
    HEAB (CLP1 Products)
    Synonyms
    Heab antibody, RGD1307679 antibody, AI462438 antibody, ACDP1 antibody, CLP-1 antibody, CGP-39 antibody, GP-39 antibody, SPC-40 antibody, SPS-40 antibody, YKL-40 antibody, HEAB antibody, hClp1 antibody, fa28a12 antibody, wu:fa28a12 antibody, clp1 antibody, cleavage and polyadenylation factor I subunit 1 antibody, CLP1, cleavage and polyadenylation factor I subunit antibody, cyclin and CBS domain divalent metal cation transport mediator 1 antibody, chitinase 3-like 1 (cartilage glycoprotein-39) antibody, cleavage and polyadenylation factor I subunit 1 L homeolog antibody, Clp1 antibody, CNNM1 antibody, CHI3L1 antibody, CLP1 antibody, clp1 antibody, clp1.L antibody
    Background

    Synonyms: ATP/GTP binding protein, CLP 1, clp1, CLP1 cleavage and polyadenylation factor I subunit homolog, CLP1, cleavage and polyadenylation factor I subunit, homolog S. cerevisiae, CLP1, yeast, homolog of, CLP1_HUMAN, hClp1, Homolog of yeast CFIA subunit Clp1p, Polynucleotide kinase Clp1, Pre mRNA cleavage complex II protein Clp1, Pre-mRNA cleavage complex II protein Clp1.

    Background: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilizing magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D, mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.

    Gene ID
    10978
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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