LTBP1 antibody (AA 221-320)

Catalog No. ABIN1714393

Product Details anti-LTBP1 Antibody

Target: LTBP1 (Latent Transforming Growth Factor beta Binding Protein 1 (LTBP1))

Binding Specificity: AA 221-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTBP1 antibody is un-conjugated

Application: ELISA

Predicted Reactivity: Human,Mouse,Rat,Cow,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LTBP1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LTBP1

Target: LTBP1 (Latent Transforming Growth Factor beta Binding Protein 1 (LTBP1))

Alternative Name: LTBP1 (LTBP1 Products)

Synonyms: ltgf-1 antibody, LTBP1 antibody, 9430031G15Rik antibody, 9830146M04 antibody, Ltbp-1 antibody, Tgfb antibody, b2b1000Clo antibody, latent transforming growth factor beta binding protein 1 S homeolog antibody, latent transforming growth factor beta binding protein 1 antibody, latent transforming growth factor beta binding protein 2 antibody, latent TGFbeta binding protein antibody, latent-transforming growth factor beta-binding protein 1 antibody, ltbp1.S antibody, ltbp1 antibody, LTBP1 antibody, LTBP2 antibody, LOC100542113 antibody, Ltbp1 antibody

Background:

Synonyms: 9430031G15Rik, 9830146M04, Latent transforming growth factor beta binding protein 1, Latent-transforming growth factor beta-binding protein 1, Latent-transforming growth factor beta-binding protein, isoform 1L, Latent-transforming growth factor beta-binding protein, isoform 1S, LBT1S, LTBP-1, Ltbp1, LTBP1_HUMAN, MGC163161, TGF-beta1-BP-1, Tgfb, Transforming growth factor beta-1-binding protein 1, Transforming growth factor beta-1-masking protein large subunit.

Background: Latent transforming growth factor-beta 1 binding protein 1 (LTBP-1), a heavy glycoprotein, is part of the platelet-derived TGF-beta 1 complex. LTBP-1 serves as an anchor for latent TGF-beta in the extracellular matrix and is a component of microfibrillar structures. Cleavage of LTBP results in LTBP-1, which may sequester latent TGF-beta in the extracellular matrix and regulate its activation. LTBP-1 mRNA is enriched in ovarian carcinoma tissues and highly expressed in serous and mucinous adenocarcinomas.

Gene ID: 4052

Pathways: Maintenance of Protein Location, Growth Factor Binding