GLE1 RNA Export Mediator Homolog (Yeast) (GLE1) antibody

Details for Product No. ABIN1714807, Supplier: Log in to see
Antigen
  • Dmel\\CG14749
  • GLE1
  • GLE1L
  • LCCS
  • LCCS1
  • hGLE1
  • Gle1l
  • 4933405K21Rik
  • AA553313
  • CG14749 gene product from transcript CG14749-RA
  • nucleoporin GLE1
  • RNA export factor Gle1
  • GLE1, RNA export mediator
  • GLE1 RNA export mediator
  • GLE1 RNA export mediator (yeast)
  • CG14749
  • CpipJ_CPIJ014147
  • SJAG_03847
  • GLE1
  • Gle1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
50
19
17
2
1
1
1
1
1
1
Host
Rabbit
44
6
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
46
29
26
19
14
8
4
1
1
1
Options
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Immunogen KLH conjugated synthetic peptide derived from human GLE1
Isotype IgG
Purification Purified by Protein A.
Alternative Name Gle1 (GLE1 Antibody Abstract)
Background

Protein transport across the nucleus is a selective, multi-step process involving several cytoplasmic factors that mediate protein passage through the nuclear pore complex (NPC). Gle1, also known as GLE1L, is a 698 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the Gle1 family. Expressed as two alternatively spliced isoforms, Gle1 associates with the NPC and is required for the transport of poly(A)-containing mRNAs from the nucleus to the cytoplasm. Defects in the gene encoding Gle1 are the cause of lethal congenital contracture syndrome type 1 (LCCS1) and lethal arthrogryposis with anterior horn cell disease (LAAHD), the former of which is characterized by early fetal hydrops and akinesia, micrognatia, pulmonary hypoplasia, pterygia and prenatal death, while the latter is associated with respiratory failure.

Synonyms: GLE 1, GLE1, GLE1 like protein, GLE1 like RNA export mediator, GLE1 RNA export mediator homolog, GLE1 RNA export mediator like yeast, GLE1-like protein, GLE1_HUMAN, GLE1L, hGLE1, LCCS 1, LCCS, LCCS1, Nucleoporin GLE1.

Gene ID 2733
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-GLE1 RNA Export Mediator Homolog (Yeast) (GLE1) antibody (ABIN1714807) Paraformaldehyde-fixed, paraffin embedded rat testis, Antigen retrieval by boiling in...
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