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MUC16 antibody
CA125
Reactivity: Human
ELISA, WB, IHC (p), FACS
Host: Mouse
Monoclonal
X75
unconjugated
Product Details anti-MUC16 Antibody
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Target
See all MUC16 (CA125) Antibodies
MUC16 (CA125)
(Mucin 16, Cell Surface Associated (CA125))
Reactivity
All reactivities for MUC16 antibodies
Human
Host
All hosts for MUC16 antibodies
Mouse
Clonality
All clonalities for MUC16 antibodies
Monoclonal
Conjugate
All conjugates for MUC16 antibodies
This MUC16 antibody is un-conjugated
Application
All applications for MUC16 antibodies
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
Specificity
Reacts with human CA-125.
Purification
Purified
Immunogen
CA-125 purified from ovarian carcinoma cells.
Clone
X75
Isotype
IgG1
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Discover our top product CA125 Primary Antibody
Alternatives
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Application Details
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Application Notes
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only: FC (0.1 μg for 106 cells) IHC-P (1 - 5 μg/mL) WB (1 - 5 μg/mL) Positive control: Positive control: OVCAR3 ovarian adenocarcinoma cells.
Restrictions
For Research Use only
Handling
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Buffer
10 mM Tris buffer, pH 7.5, 0.15 M NaCl, 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Dilute in PBS or medium that is identical to that used in the assay system.
Storage
-20 °C
Storage Comment
These antibodies are stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Target Details for MUC16
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Target
MUC16 (CA125)
(Mucin 16, Cell Surface Associated (CA125))
Alternative Name
CA-125 (CA125 Products )
Synonyms
CA125 antibody, 1110008I14Rik antibody, Ca125 antibody, Gm1480 antibody, RGD1308422 antibody, MUC16 antibody, mucin 16, cell surface associated antibody, mucin 16 antibody, mucin-16 antibody, MUC16 antibody, Muc16 antibody, LOC476718 antibody, LOC712735 antibody
Background
CA-125 (cancer antigen 125, carcinoma antigen 125, or carbohydrate antigen 125) also known as mucin 16 or MUC16 is encoded by the MUC16 gene in humans.MUC16 is a member of the mucin family of glycoproteins. CA-125 is most consistently elevated in epithelial ovarian cancer, but can be expressed in a number of gynecologic (endometrial, fallopian tube) and nongynecologic (pancreatic, breast, colon and lung) cancers. It may also be elevated in cases of benign abnormalities such as endometriosis. MUC16, mucin 16 cancer antigen 125, carcinoma antigen 125, carbohydrate antigen 125
Gene ID
94025
UniProt
Q8WXI7
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