IL-6 Receptor antibody

Catalog No. ABIN1722450

Product Details anti-IL-6 Receptor Antibody

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Reacts with human Interleukin-6 Receptor α subunit, IL-6 Ra, IL-6 R, a 80 kDa protein

Cross-Reactivity (Details): Recognizes both soluble and membrane bound IL-6 R

Purification: Purified

Immunogen: CD126/gp80 transfected CHO cell line

Clone: B-R6

Isotype: IgG1

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
FC(10 μL to label 106 cells or 100 μL of whole blood)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 tests/mL

Buffer: PBS, BSA 1 % , Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Stable at +2-8°C for 12 months For longer storage, freeze aliquots

Expiry Date: 12 months

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: CD126 / IL-6R (IL6R Products)

Synonyms: IL6R antibody, il-6ra antibody, CD126 antibody, IL-6R-1 antibody, IL-6RA antibody, IL6Q antibody, IL6RA antibody, IL6RQ antibody, gp80 antibody, IL6R1 antibody, Il6ra antibody, IL-6Ralpha antibody, IL-6R antibody, Il6r antibody, interleukin 6 receptor antibody, interleukin 6 receptor, alpha antibody, IL6R antibody, il6r antibody, Il6r antibody, Il6ra antibody

Background: CD126 is a part of IL-6R that is unable to transduce signal by itself but only in association with IL6ST.

Gene ID: 3570

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints