ADAM10 antibody (ADAM Metallopeptidase Domain 10)

Details for Product anti-ADAM10 Antibody No. ABIN1731511
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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51
46
3
2
1
Host
Rabbit
104
13
4
1
Clonality
Polyclonal
Conjugate
This ADAM10 antibody is un-conjugated
5
3
3
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
82
35
21
13
13
11
10
8
5
2
2
1
1
Options
Immunogen Synthetic peptide corresponding to amino acids 732 to 748 of human ADAM10. This sequence is identical to those of bovine and rat origins and differs from that of mouse ADAM10 by one amino acid.
Isotype IgG
Specificity Reacts with human ADAM10. Predicted to cross-reacts with bovin, mouse and rat protein.
Purification Purified
Antigen
Alternative Name ADAM10 (ADAM10 Antibody Abstract)
Background ADAM 10 is an endopeptidase involved in cell-cell signaling and many other biological processes

Disintegrin and metalloproteinase domain-containing protein 10, ADAM 10 CDw156 Kuzbanian protein homolog Mammalian disintegrin-metalloprotease CD156c Gene name: : ADAM10, KUZ, MADM
Gene ID 102
UniProt O14672
Pathways Notch Signaling, EGFR Signaling Pathway
Application Notes Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
ELISA1:100-1:2000 ICC/IF2 μg/mL IHC-P1:500 WB 1 - 10 μg/mL

Positive control: K562 or Jurkat cells
Restrictions For Research Use only
Format Liquid
Buffer PBS, pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Dilute in PBS or medium which is identical to that used in the assay system.
Storage -20 °C
Storage Comment Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.
Expiry Date 6 months