Pyruvate Dehydrogenase Kinase (AA 300-400) antibody
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- Target
- Pyruvate Dehydrogenase Kinase
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Binding Specificity
- AA 300-400
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- Reacts with the human PDK1
- Cross-Reactivity
- Mouse (Murine), Cow (Bovine), Zebrafish, Chicken, Pig (Porcine)
- Cross-Reactivity (Details)
- Predicted to cross react with mouse, rat, bovine (100 % ), chicken (92 %), porcine (91 %), primate (100 %) and zebrafish (91 %).
- Purification
- Purified
- Immunogen
- Synthetic peptide made to an internal portion of the human PDK1 protein sequence (between residues 300-400)
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- Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB0.5 - 2 μg/mL - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Tris-glycine, NaCl 150 mM buffer, Sodium azide 0.05 %
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- Target
- Pyruvate Dehydrogenase Kinase
- Background
- Pyruvate dehydrogenase kinase isoform 1 (PDK1) inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
- Gene ID
- 5163
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