CYP24A1 antibody (AA 481-490)

Catalog No. ABIN1804496

Product Details anti-CYP24A1 Antibody

Target: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Binding Specificity: AA 481-490

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CYP24A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human CYP24A1 / CYP24. This antibody is expected to recognize both reported isoforms (NP_000773.2, NP_001122387.1).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-RKYDIQATDN from an internal region of human CYP24A1 / CYP24 (NP_000773.2, NP_001122387.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Marmoset, Elephant, Panda, Horse (90%), Rat, Dog, Bat, Xenopus (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000), WB (0.1 - 0.3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx 50kD band observed in Human and Rat Liver lysates (calculated MW of 51.2kD according to NP_001122387.1). Recommended concentration: 0.1-0.3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CYP24A1

Target: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Alternative Name: CYP24 / CYP24A1 (CYP24A1 Products)

Synonyms: CP24 antibody, CYP24 antibody, HCAI antibody, P450-CC24 antibody, 24-OHase antibody, Cyp24 antibody, 25-hydroxyvitaminD324-hydroxylase antibody, VITD12 antibody, CP450CC24 antibody, cytochrome P450 family 24 subfamily A member 1 antibody, cytochrome P450, family 24, subfamily a, polypeptide 1 antibody, cytochrome P450, family 24, subfamily A, polypeptide 1 antibody, CYP24A1 antibody, Cyp24a1 antibody

Background: Name/Gene ID: CYP24A1
Family: Cytochrome P450

Synonyms: CYP24A1, 24-OHase, CP24, CYP24, Cytochrome P450-CC24, Exo-mitochondrial protein, HCAI, p450-CC24, Vitamin D 24-hydroxylase, Cytochrome P450 24A1, Vitamin D(3) 24-hydroxylase

Gene ID: 1591

NCBI Accession: NP_000773, NP_001122387

UniProt: Q07973

Pathways: Metabolism of Steroid Hormones and Vitamin D