MUC2 antibody

Catalog No. ABIN181865

Product Details anti-MUC2 Antibody

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody recognises the MUC2 mucin, and shows no cross-reactivity with MUC1, MUC3 or MUC4 mucins. In tissue sections SM1709 recognises colon, liver and prostate tissues strongly. The antibody recognises malignant colonic mucosa as well as normal mucosa.

Purification: Affinity Chromatography on Protein G

Immunogen: MUC2 tandem repeat peptide. Spleen cells from immunised Balb/c mice were fused with cells of a mouse NSO myeloma cell line.

Clone: 996-1

Isotype: IgG1

Application Details

Application Notes: Western Blot. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections. Recommended Positive Control: Normal colon
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MUC2

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Alternative Name: Mucin-2 (MUC2 Products)

Synonyms: 2010015E03Rik antibody, MCM antibody, wnn antibody, MLP antibody, MUC-2 antibody, SMUC antibody, HH-Muc antibody, mucin 2 antibody, mucin 2, oligomeric mucus/gel-forming antibody, mucin-2 antibody, Muc2 antibody, MUC2 antibody, LOC100724045 antibody

Background: MUC2 expression is detected in such human tissues as normal colon, breast, prostate, salivary gland and in gastrointestinal, colonic, breast and prostate neoplasia. This antibody labels MUC2 in normal colon and colonic carcinomas where it produces intense perinuclear staining in goblet cells. It also reacts with normal and neoplastic breast tissues and with prostate adenocarcinoma.Synonyms: Intestinal mucin-2, MUC-2, MUC2, SMUC

Gene ID: 4583

NCBI Accession: NP_002448

UniProt: Q02817