LTBR antibody

Catalog No. ABIN1821088

Product Details anti-LTBR Antibody

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LTBR antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Human CD18 the beta 2 integrin subunit (CD18) adhesion molecule of about 95kD. Blocks binding of ICAM-1 and ICAM-3 to LFA-1.

Purification: Affinity purified

Immunogen: Human peripheral blood monocytes.

Clone: IB4

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo

Usage: Flow Cytometry: 5x10e5 cultured human HPB-MLT cells per tube were incubated 45 min on ice with 80 μL of anti-CD18 antibody at a concentration of 5 μg/mL. Cells were washed twice and incubated with Goat anti-Mouse IgG/FITC, after which they were washed three times, fixed and analyzed by FACS. Cells stained positive with a mean shift of 1.52 log10 fluorescent units when compared to a Mouse IgG2a negative control at a similar concentration.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride. No preservative added

Preservative: Without preservative

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for LTBR

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Alternative Name: LTBR (LTBR Products)

Synonyms: AI256028 antibody, CD18 antibody, LTbetaR antibody, Ltar antibody, TNF-R-III antibody, TNFCR antibody, TNFR-RP antibody, TNFR2-RP antibody, TNFRrp antibody, Tnfbr antibody, Tnfrsf3 antibody, D12S370 antibody, LT-BETA-R antibody, TNFR3 antibody, TNFRSF3 antibody, lymphotoxin beta receptor antibody, lymphotoxin B receptor antibody, Ltbr antibody, LTBR antibody

Background: Name/Gene ID: LTBR
Family: TNF Receptor

Synonyms: LTBR, D12S370, CD18, LT-BETA-R, Lymphotoxin B receptor, Lymphotoxin-beta receptor, TNFR3, TNF-R-III, TNF-RIII, TNFCR, TNFRSF3, TNFR-III, TNFR-RP, TNFR2-RP

Gene ID: 4055

UniProt: P36941

Pathways: NF-kappaB Signaling