RFC4 antibody (AA 18-293)

Catalog No. ABIN1886121

Product Details anti-RFC4 Antibody

Target: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Binding Specificity: AA 18-293

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 18 and 293 of RFC4

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for RFC4

Target: RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))

Alternative Name: RFC4 (RFC4 Products)

Synonyms: 44.t00003 antibody, 21.m03053 antibody, rfc4 antibody, A1 antibody, AI894123 antibody, AU040575 antibody, RFC37 antibody, rfc2 antibody, replication factor C subunit 4 antibody, Replication factor C subunit 4 antibody, replication factor C (activator 1) 4 antibody, replication factor C subunit 4 L homeolog antibody, PFL2005w antibody, EHI_167150 antibody, TP03_0432 antibody, Tb11.01.1310 antibody, BBOV_IV002210 antibody, rfc4 antibody, rfc-4 antibody, Rfc4 antibody, RFC4 antibody, rfc4.L antibody

Background: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC).RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD.This gene encodes the 37 kD subunit.This subunit forms a core complex with the 36 and 40 kDa subunits.The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system.Alternatively spliced transcript variants encoding the same protein have been reported.[provided by RefSeq]

Molecular Weight: 40 kDa

Gene ID: 5984

NCBI Accession: NM_002916, NP_002907

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA