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alpha Actinin 4 antibody (AA 206-512)

ACTN4 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1886181
  • Target See all alpha Actinin 4 (ACTN4) Antibodies
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Binding Specificity
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 206-512
    Reactivity
    • 84
    • 44
    • 41
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 77
    • 7
    Rabbit
    Clonality
    • 66
    • 17
    Polyclonal
    Conjugate
    • 52
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This alpha Actinin 4 antibody is un-conjugated
    Application
    • 65
    • 29
    • 26
    • 17
    • 16
    • 14
    • 12
    • 12
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 206 and 512 of alpha Actinin 4
    Top Product
    Discover our top product ACTN4 Primary Antibody
  • Application Notes
    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.500
    Immunofluorescence: 1.100-1.200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    Biohazard Informations: This product contains thimerosal which is hazardous.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Target
    alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
    Alternative Name
    alpha Actinin 4 (ACTN4 Products)
    Synonyms
    fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody
    Background
    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins.Alpha actinin is an actin-binding protein with multiple roles in different cell types.In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane.In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.Mutations in this gene have been associated with focal and segmental glomerulosclerosis.[provided by RefSeq]
    Molecular Weight
    105 kDa
    Gene ID
    81
    Pathways
    Proton Transport
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