PSMF1 antibody (AA 209-271)

Catalog No. ABIN1886185

Product Details anti-PSMF1 Antibody

Target: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Binding Specificity: AA 209-271

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMF1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 209 and 271 of Proteasome inhibitor PI31 subunit

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 x PBS, 40 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for PSMF1

Target: PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))

Alternative Name: Proteasome inhibitor PI31 subunit (PSMF1 Products)

Synonyms: PI31 antibody, AW048666 antibody, BC012260 antibody, zgc:92785 antibody, proteasome inhibitor subunit 1 antibody, proteasome (prosome, macropain) inhibitor subunit 1 antibody, PSMF1 antibody, Psmf1 antibody, psmf1 antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators.Alternative transcript variants have been identified for this gene.[provided by RefSeq]

Molecular Weight: 30 kDa

Gene ID: 9491

NCBI Accession: NP_006805, NM_006814

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA