ARHGEF18 antibody (AA 612-802)

Catalog No. ABIN1886579

Product Details anti-ARHGEF18 Antibody

Target: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Binding Specificity: AA 612-802

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF18 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 612 and 802 of ARHGEF18

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for ARHGEF18

Target: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Alternative Name: ARHGEF18 (ARHGEF18 Products)

Synonyms: arhgef18 antibody, wu:fc21e04 antibody, wu:fj05f11 antibody, zgc:85686 antibody, P114-RhoGEF antibody, AI467246 antibody, D030053O22Rik antibody, rho/rac guanine nucleotide exchange factor (GEF) 18a antibody, Rho/Rac guanine nucleotide exchange factor (GEF) 18 antibody, Rho/Rac guanine nucleotide exchange factor 18 antibody, rho guanine nucleotide exchange factor 18 antibody, rho/rac guanine nucleotide exchange factor (GEF) 18 antibody, arhgef18a antibody, ARHGEF18 antibody, LOC100027283 antibody, Arhgef18 antibody

Background: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions.These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility.Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs).The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family.Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain.Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq]

Molecular Weight: 114 kDa

Gene ID: 23370

NCBI Accession: NP_056133, NM_015318

Pathways: Neurotrophin Signaling Pathway