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TYK2 antibody (AA 680-1176)
TYK2
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TYK2 Antibody
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Target
See all TYK2 Antibodies
TYK2
(Tyrosine Kinase 2 (TYK2))
Binding Specificity
All epitopes for TYK2 antibodies
AA 680-1176
Reactivity
All reactivities for TYK2 antibodies
Human
Host
All hosts for TYK2 antibodies
Rabbit
Clonality
All clonalities for TYK2 antibodies
Polyclonal
Conjugate
All conjugates for TYK2 antibodies
This TYK2 antibody is un-conjugated
Application
All applications for TYK2 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Purification
Purified by antigen-affinity chromatography.
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 680 and 1176 of TYK2
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Alternatives
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Application Details
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Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for TYK2
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Target
TYK2
(Tyrosine Kinase 2 (TYK2))
Alternative Name
TYK2 (TYK2 Products )
Synonyms
JTK1 antibody, tyrosine kinase 2 antibody, TYK2 antibody, Tyk2 antibody
Background
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families.This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits.It is also component of both the type I and type III interferon signaling pathways.As such, it may play a role in anti-viral immunity.A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.[provided by RefSeq]
Molecular Weight
134 kDa
Gene ID
7297
NCBI Accession
NM_003331 , NP_003322
Pathways
JAK-STAT Signaling , Hepatitis C
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