AP3M1
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
Biotin
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
AP3M1
(Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))
1200013D09Rik antibody, C78982 antibody, R75378 antibody, P47a antibody, adaptor related protein complex 3 mu 1 subunit antibody, adaptor-related protein complex 3, mu 1 subunit antibody, AP3M1 antibody, Ap3m1 antibody
Background
The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2).The complex is associated with the Golgi region as well as more peripheral structures.It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.AP3M1 is highly homologous to AP3M2 but is the preferred binding partner to the YQRL motif from the cytosolic domain of TGN38.AP3M1 has also been shown to interact with the HIV-1 virulence protein Nef. Synonyms: Adaptor-related protein complex 3 mu-1 subunit, AP-3 complex subunit mu-1, mu3A