SPRED3 antibody (Center)

Catalog No. ABIN1887634

Product Details anti-SPRED3 Antibody

Target: SPRED3 (Sprouty-Related, EVH1 Domain Containing 3 (SPRED3))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPRED3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity (Details): This Spred3 antibody is predicted to have no cross-reactivity to Spred1 or Spred2.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the center of the human Spred3.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for SPRED3

Target: SPRED3 (Sprouty-Related, EVH1 Domain Containing 3 (SPRED3))

Alternative Name: Spred3 (SPRED3 Products)

Synonyms: si:ch211-255l12.2 antibody, RGD1311713 antibody, Eve-3 antibody, spred-3 antibody, AW047143 antibody, D130060H24Rik antibody, Spred-3 antibody, sprouty related EVH1 domain containing 3 antibody, sprouty-related, EVH1 domain containing 3 antibody, SPRED3 antibody, spred3 antibody, Spred3 antibody

Background: Spred3 is a member of the Sprouty family, a group of proteins that act as negative regulators during development.Like Spred1 and Spred2, Spred3 contains and EVH1 domain in its amino terminus and a Sprouty-related cysteine-rich (SPR) domain in its C-terminus, but does not possess a functional c-kit binding domain (KBD).The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis.Although Spred3 was initially reported to be expressed in brain, at least one report also indicates that Spred3 can be found in liver.At least two isoforms of Spred3 are known to exist.
Synonyms: Sprouty-related EVH1 domain-containing protein 3, EVE-3

NCBI Accession: NP_001035987