NLRP14 antibody (N-Term)

Catalog No. ABIN1888001

Product Details anti-NLRP14 Antibody

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the amino terminus of human NALP14.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for NLRP14

Target: NLRP14 (NLR Family, Pyrin Domain Containing 14 (NLRP14))

Alternative Name: NALP14 (NLRP14 Products)

Synonyms: 4921520L01Rik antibody, GC-LRR antibody, Nalp-iota antibody, Nalp14 antibody, Nalp14l antibody, NALP14 antibody, CLR11.2 antibody, NOD5 antibody, PAN8 antibody, NLR family, pyrin domain containing 14 antibody, NLR family pyrin domain containing 14 antibody, Nlrp14 antibody, NLRP14 antibody

Background: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction.Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain.While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.
Synonyms: NACHT, LRR and PYD domains-containing protein 14, NLRP14, CLR11.2, PAN8, NOD5, GC-LRR

NCBI Accession: NP_789792

Pathways: Inflammasome