ORMDL1 antibody

Catalog No. ABIN1888238

Product Details anti-ORMDL1 Antibody

Target: ORMDL1 (ORM1-Like 1 (ORMDL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORMDL1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity (Details): ORMDL1 antibody is predicted to not cross-react with other ORMDL protein family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide of human ORMDL1.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for ORMDL1

Target: ORMDL1 (ORM1-Like 1 (ORMDL1))

Alternative Name: ORMDL1 (ORMDL1 Products)

Synonyms: adoplin-1 antibody, C730042F17Rik antibody, ORMDL sphingolipid biosynthesis regulator 1 S homeolog antibody, ORMDL sphingolipid biosynthesis regulator 1 antibody, ORM1-like 1 (S. cerevisiae) antibody, ormdl1.S antibody, ORMDL1 antibody, Ormdl1 antibody

Background: The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation.Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD).Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD.ORMDLs have recently been identified as a potential risk factor for childhood asthma.
Synonyms: Adoplin-1, FLJ44364, HSPC202, ORM1-like protein 1

NCBI Accession: NP_057551