PDGFRB antibody (Extracellular Domain)
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- Target See all PDGFRB Antibodies
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human, Monkey, Baboon
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PDGFRB antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Recognizes the extracellular domain of the human PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. Does not recognize PDGF receptor alpha. PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
- No Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
- Purification
- Protein G purified
- Immunogen
- Human skin fibroblast cell membrane extracts.
- Clone
- PR7212
- Isotype
- IgG1
- Top Product
- Discover our top product PDGFRB Primary Antibody
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- Application Notes
- Approved: Flo (25 μg/mL), IHC, IHC-Fr, IHC-P (25 μg/mL), IP, WB
- Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
- Alternative Name
- PDGFRB / PDGFR beta (PDGFRB Products)
- Synonyms
- AI528809 antibody, CD140b antibody, PDGFR-1 antibody, Pdgfr antibody, CD140B antibody, IBGC4 antibody, JTK12 antibody, PDGFR antibody, PDGFR1 antibody, platelet derived growth factor receptor, beta polypeptide antibody, platelet derived growth factor receptor beta antibody, Pdgfrb antibody, PDGFRB antibody
- Background
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Name/Gene ID: PDGFRB
Subfamily: PDGF Receptor
Family: Protein Kinase
Synonyms: PDGFRB, CD140B, Beta pdfgr, Beta type PDGFR, BPDGFR, CD140b antigen, IBGC4, JTK12, PDGF-beta R, PDGF-R-beta, PDGFR, PDGFRbeta, PDGF receptor beta, PDGF-R, PDGFbetaR, PDGFR Beta, PDGFR-1, PDGFR-beta, BetaPDGFR, Pdgf beta-receptor, PDGFR1, PDGFRB/CEV14 fusion gene - Gene ID
- 5159
- Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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