COL4A1 antibody (AA 30-167) (Biotin)
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- Target See all COL4A1 Antibodies
- COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))
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Binding Specificity
- AA 30-167
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This COL4A1 antibody is conjugated to Biotin
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Collagen alpha-1(IV) chain protein (30-167AA)
- Isotype
- IgG
- Top Product
- Discover our top product COL4A1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))
- Alternative Name
- COL4A1 (COL4A1 Products)
- Synonyms
- col4a1 antibody, wu:fc02g11 antibody, HANAC antibody, ICH antibody, POREN1 antibody, arresten antibody, Bru antibody, Col4a-1 antibody, Del(8)44H antibody, Raw antibody, Svc antibody, collagen, type IV, alpha 5 (Alport syndrome) antibody, collagen type IV alpha 1 chain antibody, collagen, type IV, alpha 1 antibody, col4a5 antibody, COL4A1 antibody, Col4a1 antibody
- Background
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Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a \'chicken-wire\' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
Aliases: Arresten antibody, BSVD antibody, CO4A1_HUMAN antibody, COL4A1 antibody, COL4A1 NC1 domain antibody, COL4A2 antibody, COL4A3 antibody, COL4A4 antibody, COL4A5 antibody, collagen alpha-1(IV) chain antibody, Collagen IV Alpha 1 Polypeptide antibody, Collagen IV Alpha 2 Polypeptide antibody, Collagen Of Basement Membrane Alpha 1 Chain antibody, Collagen Of Basement Membrane Alpha 2 Chain antibody, Collagen Type IV Alpha 1 antibody, collagen type IV alpha 1 chain antibody, Collagen Type IV Alpha 2 antibody, Collagen Type IV Alpha 3 antibody, Collagen Type IV Alpha 4 antibody, Collagen Type IV Alpha 5 antibody, RATOR antibody
- UniProt
- P02462
- Pathways
- Skeletal Muscle Fiber Development, Growth Factor Binding
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