TGFB1 antibody
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- Target See all TGFB1 Antibodies
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TGFB1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Neutralization (Neut), Functional Studies (Func)
- Specificity
- Western Blot demonstrated reactivity to either dimeric (25kD) or monomeric (12.5kD) molecules of TGF-b under non-reducing and reducing condition, respectively. Recognizes both human platelet-derived and recombinant TGF-b in enzyme-linked in ELISA.
- Purification
- Protein G purified
- Immunogen
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TGF-b from human platelets.
Type of Immunogen: Purified protein - Isotype
- IgG1 kappa
- Top Product
- Discover our top product TGFB1 Primary Antibody
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- Application Notes
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Approved: ELISA, Func, IHC, Neut, WB
Usage: Suitable for use in ELISA, Neutralization, Immunohistochemistry and Western Blot. Neutralization: Neutralizes TGF-b activity in vitro inhibition assay of CCL/64 cell growth and also neutralize the growth promoting action of TGF-b in the NRK-49F colony forming assays. The effect of microinjection of this MAb into one blastomere of two cell stage Xenopus embryos indicated that this antibody was able to neutralize effectively the bioactivity of TGF-b in vivo. Immunohistochemistry: Used to locate TGF-b within tissues. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.0, 40 % glycerol.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
- Alternative Name
- TGFB1 / TGF Beta 1 (TGFB1 Products)
- Synonyms
- CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGF-beta antibody, TGF-BETA-1 antibody, TGF-beta5 antibody, ced antibody, dpd1 antibody, lap antibody, tgf-beta antibody, tgfb antibody, tgfb5 antibody, tgfbeta antibody, TGF-beta1 antibody, TGFbeta1 antibody, Tgfb antibody, Tgfb-1 antibody, ai39657 antibody, tgfb1 antibody, wu:fb13a07 antibody, xx:ai39657 antibody, TGFB1 antibody, csd antibody, cdb1 antibody, cdg2 antibody, csd1 antibody, csd2 antibody, csd3 antibody, ebmd antibody, lcd1 antibody, bigh3 antibody, cdgg1 antibody, betaig-h3 antibody, TGFB4 antibody, transforming growth factor beta 1 antibody, transforming growth factor beta-1 antibody, transforming growth factor beta 1 L homeolog antibody, transforming growth factor, beta 1 antibody, transforming growth factor, beta 1a antibody, transforming growth factor beta induced L homeolog antibody, TGFB1 antibody, Tgfb1 antibody, tgfb1.L antibody, tgfb1a antibody, tgfbi.L antibody
- Background
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Name/Gene ID: TGFB1
Family: TGF beta
Synonyms: TGFB1, CED, DPD1, Diaphyseal dysplasia 1, LAP, Latency-associated peptide, TGF Beta, TGFbeta, TGF-beta 1 protein, TGF-beta-1, TGFB - Gene ID
- 7040
- UniProt
- P01137
- Pathways
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
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