FLT3LG antibody

Catalog No. ABIN205922

Product Details anti-FLT3LG Antibody

Target: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLT3LG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Specificity: Recognizes the ubiquitously expressed human growth factor Flt3-Ligand (Flt3L), a 235aa type I transmembrane glycoprotein which regulates the proliferation of early hematopoietic cells. Flt3L exists in both a membrane-bound and proteolytically cleaved soluble isoform, both of which are biologically active, and initiates cell proliferation/ differentiation signalling in co-operation with other colony stimulating factors (CSFs) and interleukins, by binding to and activating the tyrosine kinase receptor Flt3 (FLT3R), expressed highly by hematopoietic progenitor cells and stem cells.

Purification: Purified

Immunogen: Recombinant human Flt3-Ligand.

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 μg/mL), Func (0.25 - 0.75 μg/mL), WB (0.1 - 0.2 μg/mL)

Usage: ELISA: May be used in an indirect ELISA system or as a capture antibody in a sandwich ELISA for human Flt3L .

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled Water. For long term storage the addition of 0.09 % sodium azide is recommended. For functional studies do not add azide.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4.

Target Details for FLT3LG

Target: FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))

Alternative Name: FLT3LG / Flt3 Ligand (FLT3LG Products)

Synonyms: Flt3lg antibody, Ly72L antibody, FL antibody, FLT3L antibody, Vegfr3 antibody, fms related tyrosine kinase 3 ligand antibody, FMS-like tyrosine kinase 3 ligand antibody, fms-related tyrosine kinase 4 antibody, fms-related tyrosine kinase 3 ligand antibody, FLT3LG antibody, Flt3l antibody, Flt4 antibody, Flt3lg antibody

Background: Name/Gene ID: FLT3LG

Synonyms: FLT3LG, FL, Flt3 ligand, FLT3L, SL cytokine

Gene ID: 2323

Pathways: RTK Signaling