L-Selectin antibody (FITC)
-
- Target See all L-Selectin (SELL) Antibodies
- L-Selectin (SELL) (Selectin L (SELL))
-
Reactivity
- Human, Cow, Cynomolgus, Rhesus Monkey
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This L-Selectin antibody is conjugated to FITC
-
Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Recognizes human CD62L, also known a L-selectin, a 74-95kD member of the selectin family of adhesion receptors, which acts as a ligand for both CD62-P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes. CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naA-ve lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains. The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.
- Purification
- Protein G purified
- Immunogen
-
PHA stimulated lymphoblasts.
Type of Immunogen: Cells - Clone
- FMC46
- Isotype
- IgG2b
- Top Product
- Discover our top product SELL Primary Antibody
-
-
- Application Notes
-
Approved: Flo (1:1), IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. - Comment
-
Target Species of Antibody: Human
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
- Target
- L-Selectin (SELL) (Selectin L (SELL))
- Alternative Name
- SELL / L-Selectin / CD62L (SELL Products)
- Synonyms
- CD62L antibody, LAM1 antibody, LECAM1 antibody, LEU8 antibody, LNHR antibody, LSEL antibody, LYAM1 antibody, PLNHR antibody, TQ1 antibody, A.11 antibody, L-selectin antibody, LECAM-1 antibody, SELE antibody, AI528707 antibody, Lnhr antibody, Ly-22 antibody, Ly-m22 antibody, Lyam-1 antibody, Lyam1 antibody, selectin L antibody, selectin, lymphocyte antibody, SELL antibody, Sell antibody
- Target Type
- Chemical
- Background
-
Name/Gene ID: SELL
Synonyms: SELL, CD62L, CD62L antigen, LAM-1, LAM1, LECAM1, LEU8, Leukocyte adhesion molecule 1, Lyam-1, LSEL, gp90-MEL, HLHRc, PLNHR, L-selectin, Leu-8, Selectin L, LNHR, LYAM1, Lymph node homing receptor, Lymphocyte adhesion molecule 1, TQ1, Pln homing receptor - Gene ID
- 6402
-