CD42b antibody

Catalog No. ABIN207042

Product Details anti-CD42b Antibody

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD42b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Blocking Antibody (Inhibition)

Specificity: Reacts with CD42b (GPIbalpha), a 135-145 kD membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIbbeta) are composed in a disulfide linked heterodimer (CD42b/c, 160 kD), CD42b/c forms a noncovalent complex with CD42a and CD42d.

Purification: Protein G purified

Immunogen: Peripheral blood mononuclear cells of a patient suffering with CLL.

Type of Immunogen: Cells

Clone: HIP1

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, IHC, IHC-Fr, Inhb

Usage: Functional Application: The antibody HIP1 inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets and ristocetin-induced platelet agglutination.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for CD42b

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Alternative Name: GP1BA / CD42B (GP1BA Products)

Synonyms: BDPLT1 antibody, BDPLT3 antibody, BSS antibody, CD42B antibody, CD42b-alpha antibody, DBPLT3 antibody, GP1B antibody, GPIbA antibody, VWDP antibody, GP1BA antibody, GPIba antibody, GPIbalpha antibody, glycoprotein Ib platelet alpha subunit antibody, glycoprotein Ib (platelet), alpha polypeptide antibody, glycoprotein 1b, alpha polypeptide antibody, GP1BA antibody, Gp1ba antibody

Background: Name/Gene ID: GP1BA

Synonyms: GP1BA, Antigen CD42b-alpha, CD42b antigen, BDPLT3, CD42b-alpha, DBPLT3, Glycoprotein Ibalpha, GPIbA, GP-Ib alpha, gp1B, GPIb-alpha, BDPLT1, BSS, CD42B, gp1BA, VWDP

Gene ID: 2811

UniProt: P07359