Synaptophysin antibody

Catalog No. ABIN212050

This Mouse Monoclonal antibody specifically detects Synaptophysin in WB, IHC, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Synaptophysin antibody (ABIN212050)

Target: Synaptophysin (SYP)

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Synaptophysin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SY38

Product Details anti-Synaptophysin Antibody

Specificity: Recognizes synaptophysin, also known as Major synaptic vesicle protein p38. Synaptophysin is a 313 amino acid ~38kD multi pass transmembrane glycoprotein containing a single domain. Synaptophysin is characteristic of small neurosecretory vesicles and is also present in neuroendocrine cells of neuronal and epithelial phenotype. Synaptophysin is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors. Has been used to detect synaptophysin in a number of neuronal and adrenal tumors including, pheochromocytomas, ganglioneuromas, neuroendocrine tumors of epithelial origin, pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids and medullary carcinoma of the thyroid.

Purification: Protein A purified

Immunogen: Synaptophysin presynaptic vesicles.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 0.5 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for Synaptophysin

Target: Synaptophysin (SYP)

Alternative Name: SYP / Synaptophysin

Background: Name/Gene ID: SYP

Synonyms: SYP, MRX, Synaptophysin, MRXSYP

Gene ID: 6855

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity