PPP1CC antibody (AA 251-323)

Catalog No. ABIN2178643

Product Details anti-PPP1CC Antibody

Target: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Binding Specificity: AA 251-323

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1CC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PP-1G

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PPP1CC

Target: PPP1CC (Protein Phosphatase 1, Catalytic Subunit, gamma Isoform (PPP1CC))

Alternative Name: PP1C gamma (PPP1CC Products)

Synonyms: PP-1G antibody, ppp1g antibody, PP1 antibody, dis2m1 antibody, fe06g11 antibody, fi22e08 antibody, wu:fe06g11 antibody, wu:fi22e08 antibody, PP1C antibody, PPP1G antibody, Ppp1cc1 antibody, ppp1cc-a antibody, protein phosphatase 1, catalytic subunit, gamma isozyme antibody, protein phosphatase 1, catalytic subunit, gamma isoform antibody, protein phosphatase 1 catalytic subunit gamma antibody, protein phosphatase 1, catalytic subunit, gamma isozyme L homeolog antibody, ppp1cc antibody, Ppp1cc antibody, PPP1CC antibody, ppp1cc.L antibody

Background:

Synonyms: EC 3.1.3.16, PP 1G, PP-1G, PP1C gamma, PP1G, PP1G_HUMAN, PP1gamma, PPP 1G, PPP1CC, PPP1CC protein, PPP1G, Protein phosphatase 1 catalytic subunit gamma isoform, Protein Phosphatase 1 gamma 1, Protein Phosphatase 1 gamma, Protein phosphatase 1C catalytic subunit, Protein phosphatase 1C subunit, Protein phosphatase 2C gamma isoform, Serine/threonine phosphatase 1 gamma, Serine/threonine protein phosphatase PP1 gamma catalytic subunit, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit.

Background: Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The protein is involved in regulation of ionic conductances and long term synaptic plasticity. It may play an important role in dephosphorylating substrates such as the postsynaptic density associated Ca (2+)/calmodulin dependent protein kinase II.PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC (PP1C gamma), which is folded into its native form by inhibitor 2 and glycogen synthetase kinase 3, and then complexed to one or several targeting or regulatory subunits. PPP1R12A and PPP1R12B mediate binding to myosin. PPP1R3A, PPP1R3B, PPP1R3C and PPP1R3D mediate binding to glycogen.

Gene ID: 5501

Pathways: Cellular Glucan Metabolic Process, Lipid Metabolism