ITGA2 antibody (N-Term) (FITC)

Catalog No. ABIN232485

Product Details anti-ITGA2 Antibody (FITC)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Binding Specificity: N-Term

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: Recognizes the integrin alpha 2 subunit, which is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit (CD29) to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, endothelial cells, monocytes and most adherent cell lines. Species cross-reactivity: cross-reacts with Cynomolgus monkey, Baboon and Rhesus monkey.

Purification: Protein G purified

Immunogen:

Type of Immunogen: Native protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo

Usage: Suitable for use in Flow Cytometry. Flow Cytometry: Neat. Use 10 μL of the suggested working dilution to label 1 x10⁶ or 100 μL whole blood. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: ITGA2 / CD49b (ITGA2 Products)

Synonyms: BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody

Background: Name/Gene ID: ITGA2
Family: Integrin

Synonyms: ITGA2, Alpha2 integrin, BR, CD49b antigen, CD49B, Integrin alpha2, Integrin Alpha 2, Integrin alpha-2, HPA-5, VLA-2, VLAA2, VLA-2 subunit alpha, Collagen receptor, GPIa, Platelet antigen Br, Platelet glycoprotein GPIa, VLA2 receptor, alpha-2 subunit

Gene ID: 3673

UniProt: P17301

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex