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Mesothelin antibody
MSLN
Reactivity: Human
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Mesothelin Antibody
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Target
See all Mesothelin (MSLN) Antibodies
Mesothelin (MSLN)
Reactivity
All reactivities for Mesothelin antibodies
Human
Host
All hosts for Mesothelin antibodies
Rabbit
Clonality
All clonalities for Mesothelin antibodies
Polyclonal
Conjugate
All conjugates for Mesothelin antibodies
This Mesothelin antibody is un-conjugated
Application
All applications for Mesothelin antibodies
ELISA, Immunohistochemistry (IHC)
Purification
Affinity purification
Immunogen
Recombinant protein of human MSLN
Isotype
IgG
Top Product
Discover our top product MSLN Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Handling Advice
Avoid freeze / thaw cycles.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Mesothelin
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Target
Mesothelin (MSLN)
Alternative Name
MSLN (MSLN Products )
Synonyms
MPF antibody, SMRP antibody, MSLN antibody, mesothelin antibody, MSLN antibody, Msln antibody, LOC611363 antibody, LOC100524016 antibody
Background
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.
Pathways
EGFR Signaling Pathway , Positive Regulation of Peptide Hormone Secretion , Intracellular Steroid Hormone Receptor Signaling Pathway , Steroid Hormone Mediated Signaling Pathway , Carbohydrate Homeostasis , cAMP Metabolic Process , Regulation of G-Protein Coupled Receptor Protein Signaling , Positive Regulation of Endopeptidase Activity , Regulation of Carbohydrate Metabolic Process
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