PYGL antibody

Catalog No. ABIN2424021

Product Details anti-PYGL Antibody

Target: PYGL (phosphorylase, Glycogen, Liver (PYGL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYGL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Recombinant protein of human PYGL

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:30-1:150

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PYGL

Target: PYGL (phosphorylase, Glycogen, Liver (PYGL))

Alternative Name: PYGL (PYGL Products)

Synonyms: zgc:66314 antibody, GSD6 antibody, glycogen phosphorylase L antibody, phosphorylase, glycogen, liver antibody, phosphorylase, glycogen, liver S homeolog antibody, liver glycogen phosphorylase antibody, PYGL antibody, pygl antibody, pygl.S antibody, Pygl antibody

Background: This gene encodes a homodimeric protein that catalyses the cleavage of alpha-1,4-glucosidic bonds to release glucose-1-phosphate from liver glycogen stores. This protein switches from inactive phosphorylase B to active phosphorylase A by phosphorylation of serine residue 15. Activity of this enzyme is further regulated by multiple allosteric effectors and hormonal controls. Humans have three glycogen phosphorylase genes that encode distinct isozymes that are primarily expressed in liver, brain and muscle, respectively.

Molecular Weight: Calculated MW: 97 kDa

Pathways: Carbohydrate Homeostasis, Cellular Glucan Metabolic Process