Myosin VIIA antibody

Catalog No. ABIN2433419

Product Details anti-Myosin VIIA Antibody

Target: Myosin VIIA (MYO7A)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VIIA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human MYO7A

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Myosin VIIA

Target: Myosin VIIA (MYO7A)

Alternative Name: MYO7A (MYO7A Products)

Synonyms: 53D10S antibody, BG:DS00929.11 antibody, CG7595 antibody, D antibody, D2 antibody, DM7a antibody, DMyoVIIa antibody, Dm 35B antibody, DmVIIA antibody, DmVIIa antibody, Dmel\\CG7595 antibody, Dro35B antibody, ESTS:53D10S antibody, Mhc35BC antibody, MyoVIIA antibody, anon-35Bb antibody, br27 antibody, ck/MyoVIIA antibody, l(1)35Ca antibody, l(2)07130 antibody, l(2)35Ca antibody, l(2)br27 antibody, l35Ca antibody, myoVIIA antibody, stc antibody, stch antibody, myo7a antibody, MYO7A antibody, NV17859 antibody, Hdb antibody, Myo7 antibody, USH1B antibody, nmf371 antibody, polka antibody, sh-1 antibody, sh1 antibody, DFNA11 antibody, DFNB2 antibody, MYOVIIA antibody, MYU7A antibody, NSRD2 antibody, crinkled antibody, myosin VIIAa antibody, myosin VIIa antibody, myosin VIIA antibody, myosin 7A antibody, myosin-VIIa antibody, ck antibody, myo7aa antibody, LOAG_02192 antibody, MYO7A antibody, myo7a antibody, LOC663995 antibody, LOC100116446 antibody, Myo7a antibody

Background: This gene is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. This gene encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.

NCBI Accession: NP_000251

Pathways: Sensory Perception of Sound